Abstract

PURPOSE: Smoking and obesity are modifiable risk factors that have been associated with a higher prevalence of asthma, more severe asthma, and worse asthma control. These two risk factors have also been found to be associated with a reduction in the effectiveness of inhaled corticosteroids (ICS), potentially leading higher prescribed doses. To our knowledge, no study has assessed the joint impact of smoking and obesity on ICS dose The present study assessed the interaction of smoking and obesity on prescribed ICS dose in adult asthmatics.

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