Abstract
AimIn the current study the relationship between self-reported nocturnal sleep duration (NSD) and daytime sleepiness with 24-h urinary protein excretion (UPE) and 24-h urinary albumin excretion (UAE) were investigated in patients with newly diagnosed type 2 diabetes mellitus. MethodsAll patients underwent history taking, physical examination, blood pressure (BP) measurement, 12 lead electrocardiographic evaluation, routine urine analysis, biochemical analysis, 24-h urine collection to measure UAE, UPE and creatinine clearance. Self reported NSD and daytime sleepiness (using Epworth Sleepiness Scale (ESS)) were recorded for all patients. ResultsIn total 110 patients (56 male and 54 female) were included. Self reported NSD was 7.17±1.07h. Mean ESS score was 5.59±2.48. Stepwise linear regression of independent factors revealed that logarithmically converted 24-h UAE (as a dependent parameter) was related with clinical systolic BP (b: 0.01, p: 0.003), HbA1c (b: 0.082, p: 0.033), self reported NSD (b: −0.152, p: 0.004) and ESS score (b: 0.044, p: 0.043). Additionally, on the other hand, 24-h UPE was related with clinical systolic BP (b: 0.011, p: 0.001) and self reported NSD (b: −0.179, p<0.0001) in regression analysis. ConclusionIn conclusion, 24-h UAE were independently related with self reported NSD and daytime sleepiness where as 24-h UPE was related with only NSD in patients with newly diagnosed type 2 diabetic patients.
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