Abstract
Introduction: Cervical cancer is a malignancy of the cervix caused by the human papillomavirus (HPV). Cervical cancer often has no symptoms. Most patients are known to be positive for cervical cancer at an advanced stage. This study aimed to determine the relationship between the use of oral contraceptives and sexual activity with the incidence of cervical cancer at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia.
 Methods: This study was an analytic observational case-control study. A total of 37 subjects were researched as a case group and a total of 111 subjects as a control group. This study made observations of variable age, Education, work, use of oral contraceptives, and sexual activity for the first time. Data analysis was carried out using SPSS software univariate and bivariate.
 Results: Use of oral contraceptives ≥ 5 years was not significantly associated with the incidence of cervical cancer, p> 0.05. Age at first sexual intercourse <18 years was significantly associated with the incidence of cervical cancer, p<0.05. Age at first pregnancy <18 years was significantly associated with the incidence of cervical cancer, p<0.05.
 Conclusion: Sexual activity is a risk factor that plays a role in the incidence of cervical cancer at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia.
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