Abstract
Metabolic syndrome or X syndrome includes a group of metabolic and non-metabolic disorders, that increase the risk of some disease. This study aimed to determine the prevalence of metabolic syndrome in healthy subjects and patients with recurrent aphthous stomatitis (RAS) was conducted. In this cross-sectional study 33 patients with recurrent aphthous stomatitis which were referred to Department of Oral Medicine of Tabriz dental school were studied. The inclusion criteria included consent to participates in the study, lack of underlying disease associated with RAS such as Behcet’s syndrome and lack of systemic diseases. RAS patients were examined in terms of risk of the metabolic syndrome and 33 age and sex matched healthy individuals were selected and examined in terms of risk of metabolic syndrome. Data samples from check list contain demographic and laboratory findings were collected. Results showed that the prevalence of metabolic syndrome in patients with RAS (21.2%) was significantly higher than in healthy people (9.1%). (p<0.05) Female percentage of RAS patients with metabolic syndrome were 71.4 and Male percentage of RAS patients with metabolic syndrome were 28.6. Given the high prevalence of metabolic syndrome in patients with RAS, this syndrome can be considered as a risk factor for RAS.
Highlights
Recurrent aphthous stomatitis (RAS) is one of the most common lesions of the oral mucosa, affecting at least 10– 20% of the general population
Metabolic syndrome or X syndrome includes a group of metabolic and non-metabolic disorders, such as hyperglycemia, hypertriglyceridemia, hypertension, low high-density lipoprotein (HDL), and abdominal obesity
In this cross-sectional study all patients with recurrent aphthous stomatitis which were referred to Department of Oral Medicine of Tabriz dental school from March to June 2019 were examined
Summary
Recurrent aphthous stomatitis (RAS) is one of the most common lesions of the oral mucosa, affecting at least 10– 20% of the general population. RAS is characterized by repeated ulceration with defined borders, which might be single or multiple and very painful. The healing of these ulcers is slow compared to traumatic lesions. Various factors have been reported as predisposing factors or related to RAS, including genetic predisposition, immune disorders, bacterial and viral infections, food allergies, vitamins deficiency, systemic conditions, hormonal disturbances, mechanical injuries and stress. Metabolic syndrome affects 25% of the American adult population and 8.2% of the American adolescents [5]. In Iran, the prevalence of metabolic syndrome has been reported over 30% in Tehran, and 3.2% among the medical students of Kashan [5,6]
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