Abstract
On-line computation of body oxygen consumption (V̇O2) was performed in twelve (n=12) cardiac surgical patients utilizing cardiopulmonary bypass. Two in-line monitors, the CDI 400™ and CDI 100™ were interfaced with a personal computer. Arterial oxygen partial pressure, saturation and temperature from the CDI 400™ and venous saturation and hemoglobin values from the CDI 100™ enabled a real time computerized V̇O2 calculation. Paired V̇O2 and fractions of inspired oxygen (FIO) values made it possible to plot an oxygen transfer equation (OTE) for the AVECOR Affinity™ hollow fiber oxygenator. Regression analysis of 124 V̇O2-FIO2 pairs established the following relationship: V̇O2 = 368.4 * FIO2 - 15.6, with a correlation of 0.89 (p<0.001). This regression line presented as an OTE-plot suggests that the Affinity™ oxgenator is capable of transferring approximately 350 ml/min of oxygen at an FIO2 = 1.0. In conclusion, on-line CPB-monitoring interfaced with a personal computer may be used for real time V̇O2 - calculations and to establish an oxygen transfer equation of a given oxygenator.
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