The relationship between neutrophil/lymphocyte ratio and clinical and radiological findings in patients with nonfunctional adrenal incidentaloma.

Abstract

Although the data in the literature regarding the etiopathogenesis of adrenal adenomas are scarce, the neutrophil/lymphocyte ratio (NLR) is an easy-to-calculate parameter that has gained popularity in recent years as an indicator of subinflammation. In this study, we aimed to show the changes in NLR in patients with adrenal incidentaloma. The anamnesis, laboratory and radiology records of the patients with adrenal incidentaloma in the last 1 year were examined. Functional adrenal incidentalomas were excluded. The records of clinical, laboratory and radiological findings of 60 patients were examined. The mean neutrophil/lymphocyte ratio was found to be 2.49±1.29 (0.89-6.84). There was no relationship between NLR, biochemical parameters and hormone levels. A weakly positive correlation was found between NLR and mass size (p=0.04; r=0.26). Adrenal incidentaloma has become one of the clinical problems frequently encountered by endocrinologists in recent years. Even when they are nonfunctional, they are thought to be associated with various metabolic disorders and inflammation. With this study, we have captured a clue to inflammation, and we are sharing the findings described herein (Tab. 1, Ref. 28) Keywords: adrenal, neutrophil, lymphocyte.