Abstract
目的 探讨外周血淋巴细胞凋亡在病毒性心肌炎发病中的作用.方法选择临床诊断病毒性心肌炎患儿和正常小儿各25例,采用Annexin V/PI双参数法经流式细胞仪定量检测两组小儿外周血淋巴细胞凋亡百分率.结果心肌炎组患儿外周血淋巴细胞凋亡百分率[(0.697 6±0.1109)%]较正常对照组[(0.128 8±0.1069)%]明显升高(t=18.459,P＜0.001),且与心肌酶CK-MB、LDH、CK、HBDH升高程度均呈明显正相关(r=0.817,P＜0.01;r=0.785,P＜0.01;r=0.726,P＜0.01;r=0.712,P＜0.01).结论病毒性心肌炎患儿外周血淋巴细胞凋亡增加,且与心肌损害程度相关。
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