Abstract

The current article presents findings on the interaction between impulsivity features and clinical characteristics of patients with alcohol use disorders (AUD). Patients (n = 88), who were completing detoxification program for the symptoms of AUD, were recruited for the study. They completed biographical questionnaire, Penn CravingScale (PACS), self-report screening measure of the symptoms of adult ADHD (ASRS v.1.1) and underwent a series of experimental tasks (Delay Discounting Task (DDT), Stroop Task, Continuous Performance Test-Identical Pairs (CPT-IP), Tower of London (ToL)). Two distinct groups of impulsivity features were identified using clusteranalysis. One group, which was comprised of DDT and ToL measures, described the level of impulsivity during the decision-making process. The second group included Stroop task and CPT-IP measures and expressed the level of response inhibition and interference control. In addition, the model of interaction between measuresof impulsivity and clinical characteristics of patients was developed. The self-report measure of inattention and hyperactivity had significant effect on the level of craving and the duration of remission. No significant relationships were observed between DDT clinical characteristics.
 Keywords: impulsivity, alcohol use disorder, delay discounting, stroop task, Tower of London, CPT-IP, craving, ASRS

Highlights

  • Impulsivity is a multidimensional concept that encompasses physiological, behavioral, cognitive, and personality aspects and constitutes a key feature in many psychiatric disorders [7, 25]

  • The goal of the current study is to explore how multiple measures of impulsivity, response inhibition, impulsive decision-making, delay discounting, difficulties maintaining sustained attention, and results of self-report on inattention and hyperactivity and might be related to the clinical characteristics of patients with alcohol use disorders (AUD)

  • Heightened impulsivity have long been linked to the development of substance use disorders and associated with the continued use and abuse of the psychoactive substances

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Summary

Introduction

Impulsivity is a multidimensional concept that encompasses physiological, behavioral, cognitive, and personality aspects and constitutes a key feature in many psychiatric disorders [7, 25]. In non-clinical populations, greater risk-taking and non-planning characteristics [4, 8, 23], increased discounting of delays [8, 12], diminished inhibitory control [8, 22], increased urgency and sensation seeking [31], and reduced cognitive control [13] were associated with greater alcohol and other substances use. Higher levels of impulsivity, including impaired decisionmaking, poor planning, reduced inhibitory control, etc., were deemed both the predictors and consequences of alcohol and other substance use disorders ([33], Jentsch et al, 2015, [19]). MacKillop et al, (2007) and Field et al (2007) reported that the levels of impulsivity is associated with symptoms of alcohol use disorder, levels of alcohol consumption, and craving, while Robles et al (2011) found that the impulsivity features don’t covary with the severity of substance use disorder

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