Abstract
Key summary pointsAimIt is crucial to identify factors contributing to malnutrition risk in older persons in order to prevent malnutrition as far as possible.FindingsFactors that increased the risk of malnutrition were: increased levels of IL-8, osteoprotegerin (OPG), and Soluble-Receptor-For-TNF-alfa (sTNFRII; log transformed). In comparison with previous studies, in our study there was no significant difference in hsCRP and IL-6 in participants at risk of malnutrition and those who were well-nourished, nevertheless, those at risk of malnutrition had significantly higher IL-8, OPG and sTNFRII concentrations, but higher levels of IL-18.MessageThe etiopathogenesis of malnutrition in older persons is complex and our study indicated that chronic inflammation plays a probable role and should be considered in evaluating nutritional status in the geriatric population; however, it also exposes an avenue where further research is needed in order to enhance our understanding and guide comprehensive patient care.
Highlights
Nutrition plays a pivotal role in life
The most common disease was hypertension followed by coronary heart disease (CHD), chronic heart failure (CHF), osteoarthrosis, history of myocardial infarction (MI), and diabetes
A quarter of the patients were diagnosed with valve disease, mainly mitral insufficiency developed in the course of CHD and heart failure
Summary
Nutrition plays a pivotal role in life. the vast majority of nutrition-focused efforts are dedicated to the epidemic of obesity, on the other end of the spectrum, malnutrition is a significant problem posing increasing concern in our geriatric population. The term “malnutrition” is used to describe a host of nutritional abnormalities. It refers to protein–energy malnutrition that occurs when metabolic requirements chronically exceed nutritional intake, resulting in a longstanding negative balance of both energy and protein [1]. According to the Global Leadership Initiative on Malnutrition (GLIM) that was convened in January 2019, for establishing the diagnosis of malnutrition the combination of at least one phenotypic and one etiologic criterion is required [2]. Etiologic criteria include reduced food intake or assimilation and disease burden/inflammatory condition. The recommended GLIM approach uses only phenotypic criteria cut-points to provide for severity grading [2]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
