Abstract
Despite improvement in diagnosis and treatment, ischemic heart disease (IHD) remains a leading cause of mortality, driven by heart failure (HF), which is caused by left ventricle (LV) adverse remodeling. This occurs due to myocardial injury and leads to an alteration of LV geometry and increased wall stress that might also reflect at atrial level [ [1] Castelvecchio S. Pappalardo O.A. Menicanti L. Myocardial reconstruction in ischaemic cardiomyopathy. Eur. J. Cardiothorac. Surg. 2019; 55: i49-i56 Crossref PubMed Scopus (15) Google Scholar ]. Recently, LA dysfunction has been proposed as a mirror of increased LV filling pressures, which might also apply in IHD [ [2] Inoue K. Khan F.H. Remme E.W. Ohte N. Garcia-Izquierdo E. Chetrit M. et al. Determinants of left atrial reservoir and pump strain and use of atrial strain for evaluation of left ventricular filling pressure. Eur. Heart J. Cardiovasc. Imaging. 2021; 23: 61-70 Crossref PubMed Scopus (53) Google Scholar ]. Prognostic value of left atrial strain quantification from 2D ultrasound imaging in post-ischemic heart failure patients: evidence from the REMODEL-HF studyInternational Journal of CardiologyVol. 362PreviewBackground. Left atrial (LA) function can be effectively assessed by measuring longitudinal LA strain (LAS) via two-dimensional speckle tracking echocardiography (2DSTE). Here, we test 2DSTE-based LAS as marker of different left ventricle (LV) remodeling patterns and as prognostic index in ischemic heart failure (HF) candidates to surgical ventricular reconstruction.Methods. We retrospectively considered ischemic HF patients with anterior (group A, n=130) or posterior (group P, n=48) LV remodeling. Full-Text PDF
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