Abstract
Impaired insight into illness is common in schizophrenia and negatively influences medication adherence and treatment outcomes. Little is known about the trajectory of insight deficits across the lifespan in patients with schizophrenia. Insight impairment is associated with illness severity, and deficits in premorbid intellectual function (i.e. IQ), executive function, and memory. The available literature suggests the course of insight impairment follows a U-shaped curve, where insight impairment is severe during the first episode of psychosis, modestly improves over mid-life, and declines again in late-life.
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