The Relationship between Hormonal Contraceptives and Metabolic Syndrome

Abstract

Background: Metabolic syndrome (MS) in women using hormonal contraceptives (HCs) are common health hazards all over the world than that of contraceptives non users. Objective: To observe the relationship of hormonal contraceptives with metabolic syndrome. Method: This cross-sectional study was carried out in the Department of Physiology, Dhaka Medical College Hospital, Dhaka, during the period from January to 31 December, 2011. Two hundred women age ranged 20-35 years using hormonal contraceptives were included in this study group. The study group was subdivided into oral contraceptive users (Group B) and injectable contraceptive users (Group C). All the women using hormonal contraceptive were selected from Model clinic and Medicine ward in DMC and also from different areas of Dhaka city. Results: In this study, the BMI value in both oral and injectable contraceptives users were significantly (P<0.001) higher than that of contraceptive non users. Within the study groups, the BMI in oral and injectable contraceptives users for 1-5 years were significantly lower (P<0.001) than that of oral contraceptive users for 6-10 years. The waist circumference (WC) in all oral and injectable contraceptives users for 1-5 years and 6-10 years were significantly (P<0.001) higher than that of contraceptive non users. Conclusion: Percentage of distribution of subjects having metabolic syndrome was higher in women using hormonal contraceptives and increase duration of hormonal contraceptives use progressively increase the level of parameters of metabolic syndrome. So, it may be concluded that women using hormonal contraceptives are more prone to develop metabolic syndrome.