Abstract
Little is known about the pathogenesis of bradycardias in preterm infants. We therefore studied episodes of bradycardia and their relationship with apnoeic pauses and desaturations in overnight tape recordings of arterial oxygen saturation (SaO2, Nellcor N100 in beat to beat mode), breathing movements, nasal airflow and ECG from 80 preterm infants at the time of discharge from hospital (mean gestational age at birth 32.5 wk (SD 2.6 wk), and at the time of study 36.3 wk (SD 2.3 wk). A bradycardia was defined as a fall in heart rate to ≤67% of baseline level for ≥4 s, an apnoeic pause as a cessation of respiration for ≥4 s, and a desaturation as a fall in SaO2 to ≤80%. 196 bradycardias were found in 46 (58%) of the recordings.
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