The relationship between epicardial fat tissue thickness and transit time flow measurement values of coronary artery bypass grafts

Hacı Ali Uçak

doi:10.34172/jcvtr.2020.50

Abstract

Introduction: Epicardial fat tissue, the true visceral adipose depot of the heart, has been associated with changes in both cardiac function and morphology. This study aimed to show the relationship between epicardial fat tissue (EFT) thickness and graft flow dynamics in arterial and venous grafts in coronary artery bypass graft surgery (CABG). Methods: Patients underwent transthoracic echocardiography before surgery and epicardial fat thickness were evaluated. The patients were divided into two groups as EFT value <5.5 (group 1) mm and ≥5.5 (group 2) mm. One hundred eighty-one patients with a total of 434 grafts (162 arterial and272 venous) underwent isolated coronary artery bypass grafting surgery. All grafts were examined by transit time flow meter intraoperatively. Results: The mean epicardial fat tissue thickness values were 4.9±0.8 mm and 6.1±1.3 mm, respectively.Mean graft flow values of left internal mammary artery was 44.21±23.2 mL/min in group 1 and39.65 ± 19.2 mL/min in group 2 (P = 0.041). Similarly, mean graft flow values were higher in group1 in all venous grafts regardless of which vessel bypass was performed. There is a significant negative correlation between epicardial fat thickness and mean graft flow. Conclusion: Epicardial fat thickness measurement preoperatively might provide additional data for the faith of the graft.

Highlights

Epicardial fat tissue, the true visceral adipose depot of the heart, has been associated with changes in both cardiac function and morphology
Previous studies have reported that intra-operative evaluation of graft function was performed effectively with Transit time flow measurement (TTFM).5,6Albeit the relationship between epicardial fat tissue (EFT) with atherosclerotic vascular damage coronary artery is prominent
434 grafts in 181 patients who underwent elective coronary artery bypass graft surgery (CABG) surgery under general anaesthesia with cardiopulmonary bypass (CPB) were evaluated within the study

Summary

Introduction

Epicardial fat tissue, the true visceral adipose depot of the heart, has been associated with changes in both cardiac function and morphology. This study aimed to show the relationship between epicardial fat tissue (EFT) thickness and graft flow dynamics in arterial and venous grafts in coronary artery bypass graft surgery (CABG). The association between epicardial fat tissue (EFT) and cardiovascular diseases (CVDs) have been reported in previous studies.[1,2] The EFT is thought of as an independent factor in myocardial modulation and development of atherosclerosis coronary arteries, but it is not a direct functional part of the heart.[3] Today, in clinical practice, EFT thickness is a parameter that can be measured using standard 2D echocardiography efficiently. Previous studies have reported that intra-operative evaluation of graft function was performed effectively with Transit time flow measurement (TTFM).5,6Albeit the relationship between EFT with atherosclerotic vascular damage coronary artery is prominent. To investigate the relationship between EFT thickness and transit time flow quantifications of venous and arterial grafts of coronary arteries in diabetic patients is the primary purpose of the current study

Objectives

Methods

Conclusion