The relationship between different cerebral infarction areas or parts and obstructive sleep apnea syndrome

Abstract

Objective To observe the changes of the area and part of infarction in patients with cerebral infarction complicating by obstructive sleep apnea syndrome (OSAS), and investigate their relationship with OSAS. Methods 200 stroke patients were recruited out of department of neurology of our hospital from July 2015 to April 2017, all patients were monitored with polysomnography for 6 hours to 3 weeks. All patients were divided into stroke group (n=89) and stroke with OSAS group (n=111) according to the apnea hypopnea index (AHI), or anterior-circulation infarction group (n=146) and posterior-circulation infarction group (n=54), or large area infarction group (infarction area ≥5 cm, n=47) and non-large area infarction group (infarction area <5 cm, n=153). The general condition, the part of infarction, the area of infarction, NIHSS score, sleep parameters of all patients were recorded. Statistical tests were implemented with IBM SPSS22.0. Results There were 63 patients with anterior-circulation infarction (70.8%) in stroke group; there were 40 patients with anterior-circulation infarction (80.0%) in stroke with mild OSAS group; there were 25 patients with anterior-circulation infarction (75.8%) in stroke with moderate OSAS group; there were 18 patients with anterior-circulation infarction (64.3%) in stroke with severe OSAS group; there was no statistically significant difference in the ratio of anterior-circulation infarction among the four groups (P>0.05). There were 20 patients with cerebral infarction (22.5%) and 27 patients with cerebral infarction complicating by OSAS (24.3%) in large area infarction group; there were 69 patients with cerebral infarction (77.5%) and 84 patients with cerebral infarction complicating by OSAS (75.7%) in non-large area infarction group; there was no statistically significant difference (P>0.05). Conclusion The area and part of cerebral infarction may not be related to the severity of OSAS. Key words: Cerebral infarction; Obstructive sleep apnea syndrome; Anterior circulation; Posterior circulation