Abstract
PurposeTo report calculated crystalline lens power and describe the distribution of ocular biometry and its association with refractive error in older Chinese adults.MethodsRandom clustering sampling was used to identify adults aged 50 years and above in Xuhui and Baoshan districts of Shanghai. Refraction was determined by subjective refraction that achieved the best corrected vision based on monocular measurement. Ocular biometry was measured by IOL Master. The crystalline lens power of right eyes was calculated using modified Bennett-Rabbetts formula.ResultsWe analyzed 6099 normal phakic right eyes. The mean crystalline lens power was 20.34 ± 2.24D (range: 13.40–36.08). Lens power, spherical equivalent, and anterior chamber depth changed linearly with age; however, axial length, corneal power and AL/CR ratio did not vary with age. The overall prevalence of hyperopia, myopia, and high myopia was 48.48% (95% CI: 47.23%–49.74%), 22.82% (95% CI: 21.77%–23.88%), and 4.57% (95% CI: 4.05–5.10), respectively. The prevalence of hyperopia increased linearly with age while lens power decreased with age. In multivariate models, refractive error was strongly correlated with axial length, lens power, corneal power, and anterior chamber depth; refractive error was slightly correlated with best corrected visual acuity, age and sex.ConclusionLens power, hyperopia, and spherical equivalent changed linearly with age; Moreover, the continuous loss of lens power produced hyperopic shifts in refraction in subjects aged more than 50 years.
Highlights
Lens power plays an important role in the development of refractive error and usually changes along lifespan[1]
Spherical equivalent, and anterior chamber depth changed linearly with age; axial length, corneal power and axial length/corneal radius (AL/CR) ratio did not vary with age
The overall prevalence of hyperopia, myopia, and high myopia was 48.48%, 22.82%, and 4.57%, respectively
Summary
Lens power plays an important role in the development of refractive error and usually changes along lifespan[1]. Lens power decreases due to the development of myopia [5, 6]. Hyperopia increases with aging; this problem arises due to a reduction in lens power in aged population [7]. In later stages of life, cataract develops in some individuals. In such cases, there is a myopic shift in the ocular refractive error, which is attributed to an increase in the refractive power of lens[8]. Lens power changes throughout life, it undergoes significant changes in both childhood and adulthood. We find it surprising to know that a few epidemiological studies about this topic, especially in older subjects [8, 9]
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