Abstract

BackgroundThe present study aimed to explore, for a better understanding, the relationship between dysfunctional coping mechanisms, functionality, and quality of life in patients with major depression, during an acute episode and euthymic phase. 65 patients diagnosed with recurrent major depressive disorder were included in a longitudinal study, during which they were evaluated twice, clinically, for coping mechanisms, and also for different life quality areas. For the first time, all patients were assessed during an acute depressive episode and for the second time after 6 months of euthymia. Coping mechanisms were assessed with the Brief COPE scale, the severity of depression was evaluated by the Hamilton Depression Rating Scale-17 items, the quality of life with the WHOQOL-Bref, and the functionality with GAF.ResultsThe coping mechanisms, represented by self-distraction and self-blame, were identified as being significantly correlated with the areas of life quality, mental health, and general environment, for patients having an acute depressive episode. In the euthymic phase of major depression, all dysfunctional coping strategies showed statistically significant associations with the quality-of-life domains and the coping mechanism represented by disengagement was significantly correlated with the global functionality.ConclusionsRegardless of the current mood state, acute depression or euthymic phase, the dysfunctional coping mechanisms influence the level of life quality domains.

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