Abstract
Purpose: To evaluate the relationship between the integrity of inner segment /outer segment (is /os) junction in OCT and final VA in patients, treated for diabetic macular edema. Methods: In this retrospective non comparative case series, 42 eyes from 33 patients with resolved diabetic macular edema were included. All of these patients had pre and post treatment Opical coherence tomography ( OCT) images and based on final status of IS/OS junction were divided into two groups. Finally visual acuity and some other clinical findings were compared between IS/OS positive and IS/OS negative patients. Results: From these 42 patients 24 were IS/OS positive and 18 were IS/OS negative. Final visual acuity in IS/OS positive group (Log MAR 0.2667) was significantly better than IS/OS negative group ( LogMAR 0.4389 ).( P< 0.038). In this study, there was no significant difference between two groups in terms of other factors such as age, sex, duration of diabetes, type of treatment, initial VA, level of lipids, level of Hb A1c and other interfering factors. Conclusion: There is a direct link between Status of photoreceptor layer in OCT and visual acuity, meaning that patients with DME having an intact IS/OS junction will have a better visual outcome.
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