Abstract
1. 1.Pentobarbital induces rhythms in the cerebellum and red nucleus of the rabbit which are identical in form and frequency. 2. 2.Some neurons in the granular and Purkinje cell layer of the cerebellum discharge in bursts which are synchronous with the barbiturate-induced rhythm. 3. 3.Low voltage high frequency stimulation of the anterior lobe of the cerebellum suppresses the barbiturate-induced rhythm in the red nucleus. 4. 4. Unilateral destruction of the brachium conjunctivum, either ipsilateral or contralateral, does not eliminate barbiturate-induced rhythm in the red nucleus, but bilateral destruction does so. 5. 5.These findings indicate that the barbiturate-induced red nucleus rhythm originates in the cerebellum although the cerebellum itself is probably not the primary source.
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