Abstract
This study was performed to examine the effects of thyroid hormones on the erythrocyte arginase activity, serum urea and uric acid levels. The levels of serum total T3, total T4, free T3 and free T4, were measured in patients sera. The levels of erythrocyte arginase activity, serum urea and uric acid levels were examined in sera of 54 healthy control Subjects (36 F, 18 M) and 66 patients (44 F, 22 M) who had high serum thyroid hormon levels. In control group the average erythrocyte arginase activity level was 44.3±6.0 U/g Hb for female and 42.1±10.0 U/g Hb for male. There were no statistically significant differences in erythrocyte arginase activity levels between control group and hyperthyroid patients. However, there were statistically significant differences in serum urea and uric acid levels between control group and patients with hyperthyroidism. Results of this study suggest that the causes of hyperthyroidsm can also make changes in serum urea and uric and levels.
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