Abstract
This paper reports the relationship between post-operative pain and personality in patients receiving pentazocine (Fortral) for pain relief. The drug was given to 26 men with lumbar disc disease who were otherwise healthy. Peak concentrations of pentazocine in the blood occured within approximately an hour of intramuscular injection and this coincide with the time of greatest pain relief. At this point also variations in pain, if related to the Neuroticism and Extraversion dimensions of personality, were insignificant. However, as the concentration of pentazocine fell the influence of personality became obvious. Patients with either high levels of neuroticism or extraversion had more pain than their fellows and the greatest differences in pain scores occured if those with both high levels of neuroticism and extraversion were compared with the remainder. It is concluded that regular prescription of analgesic drugs of adequate potency is preferable to an “on demand” schedule and that the beneficial effects of the former in reducing patients' anxiety about relief of pain colud be enhanced by other means.
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