Abstract

Previous studies have demonstrated that sleep duration is closely associated with metabolic risk factors. However, the relationship between habitual sleep duration and blood pressure values in Japanese population has not been fully established. We performed a cross-sectional study of 1,670 Japanese male subjects to clarify the relationship between habitual sleep duration and blood pressure values. The study subjects were divided into four groups (<6, 6-, 7-, and ≥8h) according to their nightly habitual sleep duration. The rate of subjects with <6, 6-, 7-, and ≥8h sleep duration was 12.0, 37.6, 38.2, and 12.2%, respectively. Compared with the group with 7-h sleep duration (referent), the <6 and ≥8h groups had significantly greater systolic and diastolic blood pressure values. The rate of hypertensive subjects, defined as systolic blood pressure ≥140mmHg and/or diastolic blood pressure ≥90mmHg, with sleep duration of <6, 6-, 7-, and ≥8h was 13.4, 5.7, 7.5, and 13.8%, respectively. Compared with the group with 7-h sleep duration (referent), the multivariate odds ratios (95% confidence interval) of the groups with <6 and ≥8h for hypertension was 2.43 (1.40-4.20, P<0.01) and 2.28 (1.31-3.95, P<0.01), respectively, adjusted for conventional cardiovascular risk factors. The present study demonstrates that both long and short habitual sleep duration were significantly associated with high blood pressure values and hypertension occurrence in Japanese male subjects.

Highlights

  • Sleep loss, long-term sleep deprivation, and alterations in sleep duration are common in modern society [1], with evidence showing that we are sleeping on average only 6.8 h per night, which is 1.5 h less than we did 100 years ago [2]

  • The present study demonstrates that both long and short habitual sleep duration were significantly associated with high blood pressure values and hypertension occurrence in Japanese male subjects

  • Body mass index (BMI), alcohol, exercise, family history of hypertension, triglyceride, and highdensity lipoprotein (HDL)-cholesterol were significantly different among the groups

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Summary

Introduction

Long-term sleep deprivation, and alterations in sleep duration are common in modern society [1], with evidence showing that we are sleeping on average only 6.8 h per night, which is 1.5 h less than we did 100 years ago [2]. Change of sleep condition exerts deleterious effects on detectable changes in metabolic [3, 4], endocrine [5], and sympathetic tone [6]. These findings suggest that alterations of habitual sleep duration may predispose to overt change of blood pressure values. Several previous studies demonstrated that shorter sleep duration was related to hypertension, compared with subjects with 7 h of sleep per night in Caucasian populations [7,8,9,10]. Previous studies have demonstrated that sleep duration is closely associated with metabolic risk factors. The relationship between habitual sleep duration and blood pressure values in Japanese population has not been fully established

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