Abstract
Most tuberculous patients at the National Jewish Hospital are ambulated early during the course of intensive combined drug therapy. This practice is based upon the evidence that the available antimicrobial agents are sterilizing only for multiplying tubercle bacilli, and upon the evidence that most isoniazid-resistant mutants of tubercle bacilli have strictly limited pathogenicity for most tuberculous patients. Thus it is believed that bed rest, except for toxic and febrile patients, is actually contraindicated.16 Therefore, rehabilitation is initiated soon after admission and initiation of drug treatment. Formerly, a patient, after a year or two or more of hospitalization could look forward to discharge on four hours of “work tolerance”-which in practical terms seldom meant economic or social selfsufficiency but an indefinite, additional period of convalescence and dependency.
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