The register of patients suffering from heart failure in St. Petersburg ”persona-chf”: interim results

Abstract

The prevalence of heart failure is becoming global, and the number of patients is steadily increasing annually. The assessment of the number of patients suffering from heart failure in St. Petersburg, as well as their characteristics, is one of the most important tasks for which the Saint Petersburg Register of Patients Suffering from Chronic Heart Failure, PERSONA-CHF, was developed and initiated. Data analysis was performed for the period from February to May 2023. A total of 158 people comprised the sample. The Hospital for War Veterans (Saint Petersburg) participated in the pilot project. The average age of the patients was 81. 14 ± 11. 39 years. The number of points based on the assessment scale of the patient’s clinical condition was 6. 4 ± 2. 6. The average left ventricular ejection fraction was 59. 1% ± 11. 1%. Moreover, 70% of patients had a left ventricular ejection fraction of 50%, and in 23. 4% of patients, it was even higher than 65%. Comorbid pathologies prevailed: hypertension, 93%; coronary heart disease, 79. 1%; chronic kidney disease, 46. 8%; atrial fibrillation, 32. 9%; anemia, 31. 6%; and diabetes mellitus, 24. 7%. A high percentage of the presence of comorbid pathology leads to the need to modify therapy and use modern groups of drugs. Beta-blockers were most often prescribed (86. 7%), diuretics (75. 3%), mineralocorticoid receptor antagonists (62%), angiotensin-converting enzyme inhibitors (61. 4%), and angiotensin II receptor blockers (39. 2%). The appointment of modern groups of drugs, such as angiotensin receptor-non-lysine inhibitor and sodium-glucose cotransporter inhibitor 2-type, was 5. 1%. Attention was drawn to the lack of continuity in the provision of medical care and low compliance of patients with modern quadrotherapy, given its high cost for the patient. In general, the efficiency of the PERSONA-CHF registry platform is quite good and allows us to more accurately understand the epidemiological aspects of heart failure, the solution of which will make it possible to improve the quality of medical care, identify the need for necessary medicines, and reduce mortality and mortality rates. However, a much larger set of patients and a different profile of medical institutions are required for the most complete understanding of the problem of heart failure in Saint Petersburg, since the Hospital for War Veterans reflects only a small sample of patients, mainly of senile age, and several comorbid pathologies. In addition, this register requires further improvement to increase the number of connected medical organizations, expand the number of analyzed parameters, automate the process, and possibly connect artificial intelligence for data analysis.