Abstract

The main processes involved in the development of the eye are similar in all vertebrates. The modifications of structure which occur in different species involve the region of the retina below the optic disc. The upper region of the retina is therefore considered by the author as “stable” in phylogeny, the lower as “fluid.” Ontogenetically and phylogenetically the fluid lower region is younger than the stable upper region, and there is a relationship between this fact and the predominant frequency of congenital malformations in the lower part of the eye. The work represented by this paper was done under the auspices of the Medical Research Council of Great Britain. Dr. Mann, who has made very extensive studies in the embryology of the eye, is Assistant Surgeon at the Royal London Ophthalmic (Moorfields) Hospital, and Pathologist at the Central London Ophthalmic Hospital. This lecture was delivered at the Royal College of Surgeons, London, February 17, 1928. The main processes involved in the development of the eye are similar in all vertebrates. The modifications of structure which occur in different species involve the region of the retina below the optic disc. The upper region of the retina is therefore considered by the author as “stable” in phylogeny, the lower as “fluid.” Ontogenetically and phylogenetically the fluid lower region is younger than the stable upper region, and there is a relationship between this fact and the predominant frequency of congenital malformations in the lower part of the eye. The work represented by this paper was done under the auspices of the Medical Research Council of Great Britain. Dr. Mann, who has made very extensive studies in the embryology of the eye, is Assistant Surgeon at the Royal London Ophthalmic (Moorfields) Hospital, and Pathologist at the Central London Ophthalmic Hospital. This lecture was delivered at the Royal College of Surgeons, London, February 17, 1928.

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