The redox code of plants.

Abstract

Central metabolism is organised through high-flux, Nicotinamide Adenine Dinucleotide(NAD+/NADH) and NADP+/NADPH systems operating at near equilibrium. As oxygen is indispensable for aerobic organisms, these systems are also linked to the levels of reactive oxygen species, such as H2O2, and through H2O2 to the regulation of macromolecular structures and activities, via kinetically controlled sulphur switches in the redox proteome. Dynamic changes in H2O2 production, scavengingand transport, associated with development, growthand responses to the environment are, therefore, linked to the redox state of the cell and regulate cellular function. These basic principles form the 'redox code' of cells and were first defined by D. P. Jones and H. Sies in 2015. Here, we apply these principles to plants in which recent studies have shown that they can also explain cell-to-cell and even plant-to-plant signalling processes. The redox code is, therefore, an integral part of biological systems and can be used to explain multiple processes in plants at the subcellular, cellular, tissue, whole organismand perhaps even community and ecosystem levels. As the environmental conditions on our planet are worsening due to global warming, climate changeand increased pollution levels, new studies are needed applying the redox code of plants to these changes.