Abstract
Genodermatoses with a marked sun sensitivity are called photogenodermatoses. They are very rare diseases in which the photosensitivity is an early and constant symptom. The photosensitivity can be expressed as sun-induced eruptions of the exposed skin areas within hours and days, as light-induced rumor formation within years, or as both symptom complexes together. An enzymatic defect of known (xeroderma pigmentosum) or unknown character, impairing the defense against or the recovery from sun-induced skin damage, can be described as the result of a genetic defect (Table 1). In other examples (porphyrias), an inborn error of metabolism leads to accumulation of products that act as endogenous photosensitizers (Table 2). The main diseases following one or the other type of pathogenesis are presented as the main headings in this article.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
