Abstract
AbstractRats were submitted to hypoxia corresponding to 6,000 m altitude for 40—50 days. The total amount of hemoglobin, blood volume and relative blood values had been studied in hypoxia and after transfer to normal oxygen pressure. Total hemoglobin increased during hypoxia by 150—200%, relative blood values by 100%, and blood volume by 25—50%, indicating the increase of oxygen capacity of the blood and the volume of the circulatory system. 30 days after transfer to normal oxygen pressure total hemoglobin, blood volume and relative blood values had returned to normal. Thereafter relative blood values showed a transient decrease, but not the total hemoglobin. Thus the blood volume increased again. Problems in connection with the homoistatic regulation of erythropoiesis have been discussed. The body weight decreased during hypoxia by about 15%. After the period of hypoxia was over the rate of increase in body weight was faster than that of animals of the same order and body weight.
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