THE RATIONAL CHOICE OF ANTIBACTERIAL THERAPY OF URINARY TRACT INFECTION IN CHILDREN DEPENDING ON THE DISEASE, AGE AND SEX OF THE CHILD

Abstract

Objective. To establish the relationship of sensitivity to antibiotics among the core group of pathogens of urinary system infections of Enterobacteriaceae (except Proteus) with age and gender of patients among children of Chernivtsi region.Patients and methods. During 2009 – 2013 bacteriological examination of 2432 urine samples received from children, patients of medical institutions in Chernivtsi and the region, was conducted for the purpose to verify the diagnosis of «urinary tract infection» (UTI). 446 strains of bacteria of the family Eterobacteriaceae (except Proteus) were identified in etiologically significant quantities. The sensitivity of the isolated strains to antibiotics was studied. Results. The dependence of antibiotic sensitivity of the major group of UTI pathogens – enterobacteria (except Proteus) on the age of patients in case of chronic forms of the infection process, and the absence of such dependence among the strains isolated in acute forms. Conclusion. Decreased sensitivity to antibiotics occurs in a certain sequence: among children under 3 years there is a decrease in their susceptibility to penicillins, at the age of 4-6 years the beginning of reduces sensitivity to fluoroquinolones is found, and in the age group of 7-14 years – to cephalosporins.