Abstract
Ovarian reserve is established during intrauterine life, with a peak at 20 weeks of gestation. The 2D:4D ratio, which is also established during prenatal life, has been proposed as a non-invasive biomarker of the prenatal hormonal environment. It has been suggested that an intrauterine environment rich in androgens induces a development of the 2D:4D ratio < 1 while estrogen exposure during prenatal life leads to a higher 2D:4D ratio. However, whether 2D:4D ratio can be used to could predict ovarian reserve needs further investigation.
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