Abstract
Objective: to study the rate of metabolic syndrome (MS) and its components among gout patients in different regions of the Russian Federation. Subjects and methods. This cross-sectional multicenter study enrolled 2277 gout patients, including 1963 (86.2%) men and 314 (13.8%) women, from 12 independent medical centers in different regions of the Russian Federation. The patients over 18 years of age who met the classification criteria for gout, elaborated by S. Wallace et al., were included. The diagnosis of MS was established on the basis of Adult Treatment Panel III (ATP III) criteria. The presence of MS, its individual components and comorbidities were recorded. Results. The total rate of MS in the patients with gout was 57%; however, it varied substantially (from 15 to 77%) in different centers. Among the comorbidities, arterial hypertension was most common (in three fourths of the patients), coronary heart disease (CHD) and type 2 diabetes mellitus were less common (43 and 25%, respectively); 15% of the patients had sustained myocardial infarction, renal and cardiac failure was also observed in 15%. In the gout patients, MS was associated with the presence of CHD. Conclusion. The patients with gout were observed to have a high rate of MS (57%), its components, and cardiovascular diseases. The findings suggest that there is a relationship between the presence of MS and the development of CHD.
Highlights
Цель – изучение частоты метаболического синдрома (МС) и его компонентов среди больных подагрой в различных регионах Российской Федерации
Из коморбидных заболеваний наиболее часто выявлялись артериальная гипертензия (у 3/4 больных), несколько реже – ишемическая болезнь сердца (ИБС; 43%) и сахарный диабет 2-го типа (25%); инфаркт миокарда перенесли 15% больных, почечная и сердечная недостаточность наблюдалась также у 15%
The diagnosis of metabolic syndrome (MS) was established on the basis of Adult Treatment Panel III (АТР III) criteria
Summary
Цель – изучение частоты метаболического синдрома (МС) и его компонентов среди больных подагрой в различных регионах Российской Федерации. В одномоментное мультицентровое исследование включено 2277 больных подагрой из 12 независимых медицинских центров в различных регионах Российской Федерации, в том числе 1963 мужчины (86,2%) и 314 женщин (13,8%). У больных подагрой отмечена высокая частота МС (57%), его компонентов и кардиоваскулярных заболеваний. THE RATE OF METABOLIC SYNDROME AND COMORBIDITIES IN PATIENTS WITH GOUT: DATA OF A MULTICENTER TRIAL. Objective: to study the rate of metabolic syndrome (MS) and its components among gout patients in different regions of the Russian Federation. This cross-sectional multicenter study enrolled 2277 gout patients, including 1963 (86.2%) men and 314 (13.8%) women, from 12 independent medical centers in different regions of the Russian Federation. У значительной части больных определяется избыточная масса тела, выявляются нарушения липидного обмена, в том числе гипертриглицеридемия, нарушения углеводного обмена: снижение толерантности к глюкозе или сахарный диабет (СД) 2-го типа, артериальная гипертензия (АГ) [2,3,4,5,6]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
