Abstract
Background: .
 Malaria is serious vector –borne tropical diseases that remains one of the primary reasons for death in several countries . Malaria and typhoid co-infection is a major public health problem in many developing countries. Most of the co-infections treated are based on methods of diagnosis plagued with assumptions which possibly exaggerate the situation. Objective: This the aim of this work was to investigate the rate of co-infection with respect to the use of direct Widal test for diagnosing typhoid fever in Khartoum state .
 Method: This was based descriptive cross-sectional malaria of Plasmodium falaciprum and Salamoella . A total of 100 blood samples were collected from patients with a clinical of malaria positive and examined for malaria parasites and S. typhi infection.
 Results: This study was conducted in Khartoum State between 2020 to 2021 in individual form different age groups form both male and female, out of 100 samples were positive for malaria parasites(Plasmodium falciprum) by blood films (100%) and immunochormatogrphy test 80(80%) , 52(52%) of which were positive for salmonella typhiO and 18(18%) salmonella para- typhi BO by the direct Widal test.
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