Abstract
The effect of the regular use of junk-food on the morphological and functional state of the liver was studied in mature females Wistar rats. Animals of experimental groups received for a 100 days a diet that included potato chips and sweet caffeine-containing soft drinks. In the liver of rats of experimental groups dystrophic changes in hepatocytes - small-, medium- and large-droplet vacuolar dystrophy from weak to severe, were detected. Compared to the control group, rats, which consumed junk-food, had a decrease in the cell and nuclei volume and glycogen content of hepatocytes. Revealed changes reflect alteration of the liver metabolic balance and point to the development of functional changes, that provide carbohydrate-fat, water-electrolyte and protein metabolism.
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