Abstract
The Tolosa-Hunt syndrome is recurrent painful ophthalmoplegia due to nonspecific cavernous sinus inflammation. The documented incidence is one to two cases per million and bilaterality is even rarer. Delay in diagnosis might lead to permanent cranial nerve damage. Our purpose in this study is to discuss clinical and radiological features of the disease. We reported two patients whom presented with external ophthalmoplegia. The preliminary clinical diagnosis was ophthalmoplegic migraine. The primary radiological evaluation including cranial CT, cerebral angiography, magnetic resonance venography were all in normal limits. Finally MR imaging was performed which demonstrated the disease in the cavernous sinus region. We believe this article will serve not only to radiologists but a broad group of specialists including neurologists, otolaryngologists, internal medicine physicians dealing with cases of external ophthalmoplegia.
Highlights
Tolosa-Hunt syndrome (THS) is a rare disease with a documented incidence of one to two cases per million [1]
The diagnostic evaluation of those patients include haematological tests, cerebrospinal fluid studies, imaging studies and biopsy. In both cases that we presented, the preliminary diagnosis was ophthalmoplegic migraine which lead to a delay in the treatment
Tolosa was first to report a patient with total opthalmoplegia in 1954 [3]
Summary
Tolosa-Hunt syndrome (THS) is a rare disease with a documented incidence of one to two cases per million [1]. The bilaterality is even rarer with an incidence of 4.1-5 percent of all cases [1]. It is non-specific granulomatous inflammation of the cavernous sinuses which. Received: 19.07.2013, Accepted: 05.11.2013 results in external opthalmoplegia. The list of diseases which result in external opthalmoplegia is broad and need to be excluded prior to final diagnosis. It includes trauma, tumors, vascular pathologies like aneurysm and fistula, infections, diabetic opthal-
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
