Abstract

A clinically feasible method for the estimation of non-heme iron in human marrow is described. Marrow aspirates, taken from patients with various disorders, were assayed for non-heme iron, and simultaneous evaluation of the marrow squashes for depot iron was done. The concentration of marrow iron was found to be 2.7 ± 1.9 μg. per mg. marrow protein. Despite broad agreement between the two methods, correlation is not good. The quantitative chemical assay may be of value in the diagnosis and investigations of the hypo- and hyperferremic states.

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