Abstract
QT interval prolongation is a predictor of the life-threatening cardiac arrhythmias — polymorphic ventricular tachycardia (torsade de pointes). Long QT syndrome may be congenital or acquired. It is known that a wide range of both antiarrhythmic and non-cardiac medications might lead to QT interval prolongation. List of drugs that cause QT prolongation is constantly growing and being updated. The review contains current data on the clinical significance of the control of QT interval duration within drug therapy. Clinical conditions associated with an increased risk of QT interval prolongation are described. Drugs that can induce QT prolongation are also discussed.
Highlights
The QT long syndrome: clinical and diagnostic aspects QT interval prolongation is a predictor of the life-threatening cardiac arrhythmias – polymorphic ventricular tachycardia
It is known that a wide range of both antiarrhythmic and non-cardiac medications might lead to QT interval prolongation
Clinical conditions associated with an increased risk of QT interval prolongation are described
Summary
Durata intervalului QT poate crește prin utilizarea unui șir de preparate medicamentoase. The QT long syndrome: clinical and diagnostic aspects QT interval prolongation is a predictor of the life-threatening cardiac arrhythmias – polymorphic ventricular tachycardia (torsade de pointes).
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