Abstract
BackgroundPatients suffering from inflammatory bowel disease (IBD) are not systematically screened against depression as well as anxiety, although there are high prevalence and adverse influence on the quality of life. The aim of this work was to determine generalized anxiety disorder and major depressive disorder prevalence in patients with IBD, and the secondary objective was to identify patient properties linked to higher psychiatric disorder rates.ResultsWe determined anxiety and depression prevalence in 105 IBD patients (82 having ulcerative colitis and 23 suffering from Crohn’s disease) through a psychiatric interview using the Arabic version of Structured Clinical Interview for DSM IV Axis I diagnosis (SCID I), in addition to severity assessment of major depressive disorder and generalized anxiety disorder using the Hamilton Depression Scale (HAM-D) and the Hamilton Anxiety Scale (HAM-A), respectively. Patient data, disease characteristics, and drug information were also gathered. We found a high depression prevalence of 56.2% (n = 59), followed by 37.1% (n = 39), with no significant association between IBD severity and anxiety and depression severity.ConclusionDepression and/or anxiety affected a large number of IBD patients. Such psychiatric disorders’ frequency would warrant detection as well as referral to psychiatric treatment.
Highlights
Patients suffering from inflammatory bowel disease (IBD) are not systematically screened against depression as well as anxiety, there are high prevalence and adverse influence on the quality of life
Prevalence of major depressive disorder and generalized anxiety disorder in patients with IBD We revealed that 59 patients (56.2%) had major depressive disorder alone (20 patients versus 19.1% of all patients) or
IQR interquartile range; SD standard deviation; CDAI Crohn’s Disease Activity Index; Mayo score is an index for the severity of ulcerative colitis
Summary
Patients suffering from inflammatory bowel disease (IBD) are not systematically screened against depression as well as anxiety, there are high prevalence and adverse influence on the quality of life. Inflammatory bowel disease (IBD), involving ulcerative colitis and Crohn’s disease, represents one of the debilitating chronic gastrointestinal diseases that has a significant adverse influence on the physical, psychological, family, and social dimensions of patients [1]. The prevalence of depression and anxiety in patients with chronic diseases in the general population is high, but they continue to receive insufficient treatment despite their significant adverse influences on the health and life quality of patients [2]. In a recent systematic review, the combined prevalence of anxiety and depression in IBD patients were 19.1% and 21.2%, respectively [6]
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