Abstract
The science and processes of anti-glycoxidation are integral for exploring novel approaches to address health concerns. The study examines the sustainable utilization of wild edibles, Secamone emetica, as a strategic solution to address health concerns and strengthen food security. A step-by-step attenuation method in a glucose-induced glycation system was used to study the impact of phytochemical content and antioxidant capabilities on glycoxidation. The distribution of metabolites and antioxidants adheres to a pattern of stem > root > leaf. The extracts effectively reduce protein carbonyls [86.45 % SSE (Stem extract of S. emetica), 84.97 % RSE (Root extract of S. emetica), 57.34 % LSE (Leaf extract of S. emetica) vs. 53.74 % in AGEs (Advanced glycation end products)] and inhibit amyloid β-aggregation (88.64 % SSE, 84.86 % RSE, 82.70 % LSE vs. 53.74 % in AGEs). Electrophoretic mobility significantly increased (9.99 × 10–5 cm2/V.s in SSE), surpassing the negative control (7.78 × 10‐5 cm2/V.s in AGEs after 72 h). Thiol group concentrations are maintained and lower 5-hydroxymethylfurfural (HMF) impurities are observed, indicating anti-glycoxidative properties. These results are comparable to aminoguanidine, suggesting the extracts scavenge free radicals and inhibit glycoxidation's consequences. Thus, highlighting the biological capacity of S. emetica in addressing oxidative stress and glycoxidation underscores its potential benefits.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
