Abstract
By the titrations of the antibody response to the vaccinations of avian influenza (AI) and Newcastle disease (ND), the present study was conducted to evaluate the effects of Marek's disease (MD)-resistant breeding and vaccination against the immunosuppression induced by virulent Marek's disease virus (MDV). The results showed that haemagglutination inhibition (HI) titres to AI and ND in MDV-unchallenged groups were significantly higher than those of MDV-challenged groups (P<0.05), those of the resistant birds were significantly higher than those of the common birds (P<0.05) and those of the herpes virus of turkeys (HVT)-vaccinated birds were significantly higher than those of the HVT-unvaccinated birds (P<0.05). The results demonstrated that antibody responses to the vaccinations of AI and ND were significantly suppressed by MDV infection, and MD-resistant breeding and HVT vaccination could significantly increase resistance to the suppression.
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