Abstract
Cell-free virulent malignant catarrhal fever virus inactivated by either formalin or acetylethylenimine (AEI) and administered with Freund's complete adjuvant protected rabbits against two consecutive parenteral challenges with cell-free virus. However 'protected' rabbits succumbed within 20 days to later inoculation of infected rabbit lymph node suspensions. Both inactivated vaccines evoked high titres of neutralising and immunofluorescent antibody, but more of the rabbits given the AEI preparation showed pyrexia after the first challenge with cell-free virus. The degree of protection afforded was compared with that induced by inactivated antigens of other herpesviruses which cause lymphoproliferative disorders
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.