The prospective study on thyroid carcinoma correlated with urine iodine level in Urmuqi region

Abstract

Objective To investigate the association of thyroid carcinoma and urine iodine level in Urumqi region, intent to provide the evidence of individual iodine supplement of this region. Methods In this case-control study, there were 100 patients with thyroid carcinoma and 300 patients with normal thyroid function as the control group in Xinjiang Tumor Hospital between February 2012 and December 2012 as the case group. All the cases were detected for urine iodine concentration by arsenic-cerium catalytic spectrophotometry. Results The mean level of urinary iodine in the case group (272.69 μg/L) was higher than that in the control group (161.40 μg/L) (P 300 μg/L) in 34 % (34/100) patients in the case group and 10 % (30/300) patients in control group (P<0.05). Conclusion The average urinary iodine content of the thyroid carcinoma in Urmuqi region are generally higher than that of the healthy control group, which indicates that the iodine nutritional status in patients with thyroid carcinoma are better than that in the general population. The relationship between thyroid carcinoma and excessive iodine intake should be necessary for further study. Key words: Thyroid neoplasms; Urine iodine; Urmuqi