Abstract
After 95 passages in primary calf kidney cultures rinderpest virus proliferated readily in HeLa cells and produced characteristic cytopathic effects. A growth-curve experiment showed that the titre of intracellular virus was consistently 10–100 fold greater than that of free virus, thus conforming to the pattern usually described for the agents of measles and canine distemper. Whereas HeLa cultures infected with measles virus readily adsorbed erythrocytes ofCercopithecus aethiops (Vervet) andPapio sp. (Baboon), no haemadsorption was noted in rinderpest-infected cultures. The latter also failed to adsorb erythrocytes of rabbits, guinea pigs, sheep, ox and dog.
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