Abstract
The Promise and Therapeutic Potential of Human ES and iPS Cells
Highlights
Beginning with a review article on tissue engineering, the reader of this special issue will first learn about the use of human embryonic stem cells (hESCs) to generate chondrocytes, osteocytes, and mesenchymal stromal cells for bone and vascular disease therapies
Due to their inexhaustible capability to expand and wide-ranging differentiation potential, human embryonic stem cells and the less ethically controversial induced pluripotent stem cells hold great promise in serving as alternative cell sources for regenerative medicine and may offer many advantages over currently available cell-based therapies. They may help treat diseases such as atherosclerosis, diabetes, stroke, liver, kidney disease as well as a variety of hematologic and neurologic disorders. This special issue focuses on the promise and therapeutic potential of hESC/iPSCs in a wide variety of diseases
It highlights important advances as well as common problems that must be resolved before the therapeutic potential of hESC/iPSCs becomes clinical reality
Summary
Beginning with a review article on tissue engineering, the reader of this special issue will first learn about the use of hESCs to generate chondrocytes, osteocytes, and mesenchymal stromal cells for bone and vascular disease therapies. Lee,[2] Claudio Napoli,[3] Steve Oh,[4] Erin A. Patients suffering from a wide variety of diseases may benefit from cell-based therapies.
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