Abstract

The Promise and Therapeutic Potential of Human ES and iPS Cells

Highlights

  • Beginning with a review article on tissue engineering, the reader of this special issue will first learn about the use of human embryonic stem cells (hESCs) to generate chondrocytes, osteocytes, and mesenchymal stromal cells for bone and vascular disease therapies

  • Due to their inexhaustible capability to expand and wide-ranging differentiation potential, human embryonic stem cells and the less ethically controversial induced pluripotent stem cells hold great promise in serving as alternative cell sources for regenerative medicine and may offer many advantages over currently available cell-based therapies. They may help treat diseases such as atherosclerosis, diabetes, stroke, liver, kidney disease as well as a variety of hematologic and neurologic disorders. This special issue focuses on the promise and therapeutic potential of hESC/iPSCs in a wide variety of diseases

  • It highlights important advances as well as common problems that must be resolved before the therapeutic potential of hESC/iPSCs becomes clinical reality

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Summary

Introduction

Beginning with a review article on tissue engineering, the reader of this special issue will first learn about the use of hESCs to generate chondrocytes, osteocytes, and mesenchymal stromal cells for bone and vascular disease therapies. Lee,[2] Claudio Napoli,[3] Steve Oh,[4] Erin A. Patients suffering from a wide variety of diseases may benefit from cell-based therapies.

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