Abstract

Pyroptosis is a newly defined programmed cell death that associates with inflammation. Pyroptosis depends on the cysteinyl aspartate specific proteinase-1 (caspase-1), accompanied by the release of proinflammatory cytokines, mainly interleukin-1β (IL-1β) and interleukin-18 (IL-18). Unlike necrosis and apoptosis, pyroptosis is a unique way of cell death. A growing number of studies have found that pyroptosis related signaling pathway plays an important role in the diseases of central nervous system, including acute brain infection, neurodegenerative disease, acute sterile brain injury and chronic sterile central nervous system inflammation. Key words: Pyroptosis; Acute brain infections; Neurodegenerative diseases; Acute sterile brain injuries; Chronic sterile central nervous system inflammation

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.