Abstract
The standard treatments of glioblastoma include surgery, postoperative radiotherapy and concurrent and adjuvant temozolomide-based chemotherapy. Radiotherapy is directly related to the overall survival rate. Nevertheless, the standard delineation of target volume during radiotherapy remains controversial. In this article, different standpoints upon the range of delineation of tumor volume were analyzed and the recurrence pattern of glioblastoma after radiotherapy was summarized. Besides, the technical causes of the failure to accurately delineate the tumor outline were identified. It is of significance to deliver individualized delineation of target volume by referring to the clinical and pathological characteristics of each patient. Finally, the application prospect of radiotherapy in the treatment of glioblastoma was discussed in this article, aiming to enhance the accuracy of target volume delineation during radiotherapy and maximize the clinical benefits to the patients. Key words: Glioblastoma; Peritumoral edema; Target volume in radiotherapy
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