Abstract
Summary At least 10 per cent of 143 patients hospitalized with tuberculosis had an MBC less than 40 per cent of the predicted normal value. Reductions of the MBC of this degree were generally associated with severe obstructive disease and far advanced tuberculosis. The fatalities in 177 patients with an MBC less than 40 per cent of normal was three times as great as in 185 patients with a normal MBC. In the abnormally low MBC group, mortality was greater in every category of severity of pulmonary tuberculosis than in the normal MBC group. The relationship between obstructive lung disease and pulmonary tuberculosis is discussed. The results indicate that severe obstructive pulmonary disease in patients with tuberculosis considerably worsens their prognosis.
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