Abstract
ABSTRACT Objective: Tuberculosis (TB) represents one of the top ten causes of death in the world. Its insidious onset and nonspecific symptoms usually result in delayed diagnosis. The objective is to evaluate the characteristics of patients with tuberculous spondylodiscitis in follow-up at a South American reference hospital. Method: Retrospective evaluation of the medical records of patients of both sexes and between 0 and 80 years of age diagnosed with tuberculosis of the spine between 2009 and 2018. The variables were analyzed based on groups: epidemiological, clinical, laboratorial, microbiological, imaging tests and treatment. Results: Total of 26 cases, about 80.8% male, mean age 41.6 ± 22.46 years. Axial pain was the most prevalent symptom (84.6%), the VAS score was 6.85 ± 2.87. The mean time between symptom onset and diagnosis was 23.8 ± 24.1 weeks (4-96). The most affected region was the thoracic spine (50% of the cases). Most participants (61.4%) had no change in neurological function (Frankel D and E) at the beginning of treatment and after 6 months, and 84.5% improved. During treatment 34.6% required surgery and the main indication was isolated neurological deficit (55.5%). The most frequently performed procedure was decompression and arthrodesis (55.5%). The average time to cure was 12.0 ± 8.8 months (8-48). Conclusion: Disease with insidious onset, nonspecific symptoms, high frequency of negative microbiological tests in cases with the disease. A small number of the cases required surgical treatment and most of them achieved good neurological recovery. Level of evidence IV; Case series.
Highlights
Tuberculosis (TB) is a global public health issue with high morbidity, and it is one of the main causes of death in the world.[1]
The objective of this study is to evaluate the characteristics of patients with tuberculous spondylodiscitis in follow-up at a South American reference hospital
The retrospective evaluation was conducted from the medical records of patients of both sexes, from 0 to 80 years of age, who were diagnosed with spinal tuberculosis and participated in follow-up at the institution between 2009 and 2018
Summary
Tuberculosis (TB) is a global public health issue with high morbidity, and it is one of the main causes of death in the world.[1]. The causative agent, Mycobacterium tuberculosis, was isolated more than a century later by Robert Koch.[4,5]. It is the main site of osteoarticular involvement in TB, occurring in about 50% of cases, and it accounts for 1% of all cases.[6] The insidious onset and non-specific symptoms usually result in a delayed diagnosis, varying from 4 to 11 months from the onset of symptoms.[7]
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