Abstract
Aims & Objectives: To study the profile of Autosomal Dominant Polycystic Kidney Disease (ADPKD) in low lying areas of NorthIndia. This is a 2 year observation study of patients attending Nephrology department in National Institute of Medical Sciences, Shobha Nagar, Jaipur, Rajasthan, India. Material & Methods: This is a 2 year prospective study done in National Institute of Medical Sciences- a tertiary hospital in rural area close to Jaipur. All ADPKD patients attending Nephrology department were studied to know their complete profile. Results: A total of 54 ADPKD patients attended Nephrology department between Jan 2014-Jan 2016, Out of which 34 patients presented with pain abdomen, 22 patients with hypertension, 8 patients with chronic renal failure kept on medical management, 8 with Chronic Kidney Disease CKD-ESRD (End Stage Renal Disease) on maintenance hemodialysis(MHD). Out of these 8 CKD-ESRD, there were 4 incidents of AV fistula thrombosis and 1 died recently whereas 20 patients remained completely asymptomatic. Conclusion: Timely diagnosis, proper understanding of disease by patients will provide good quality of life in these patients. Low salt diet, good control of hypertension (<130/80 mm of hg) delays progression to ESRD in these patients.
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