Abstract
Two cases of recurrent peptic ulceration following subtotal gastrectomy are presented, both suggesting the diagnosis of Zollinger-Ellison syndrome. This diagnosis was confirmed histologically in the first case and not in the second. A program of surgical therapy is suggested to deal with the problem of the second case in which a clinical picture of Zollinger-Ellison syndrome was presented, but in which no tumor could be identified. We suggest that the surgical attack should be directed against the pancreas rather than the residual stomach, to interrupt the ulcerogenic tendency and provide maximal postoperative state of nutrition.
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