THE PROBLEM OF POSTOPERATIVE COGNITIVE DYSFUNCTION IN PATIENTS WITH OBESITY IN EMERGENCY SURGERY

Maisuradze Alla Maisuradze Alla

doi:10.31435/rsglobal_ws/28022021/7441

Maisuradze Alla Maisuradze Alla

Open Access

https://doi.org/10.31435/rsglobal_ws/28022021/7441

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Journal: World Science	Publication Date: Feb 20, 2021
Citations: 1	License type: CC BY 4.0

Affiliation: Kharkiv National Medical University

Abstract

The occurrence of postoperative cognitive dysfunction is a negative consequence of vascular endothelial dysfunction in patients with grade I-II obesity with appropriate metabolic shifts and comorbid background, which increases the duration of treatment and worsens the prognosis in patients with acute surgical pathology. It is important to add endothelioprotectors to the intensive care unit. L-arginine hydrochloride has been shown to be pathogenetically justified as a prophylaxis for an increase in the level of antigens to von Willebrand factor in the blood of obese patients with acute surgical pathology. Administration of this substance before and during surgery is likely to improve mental performance in the postoperative period in patients with elevated body mass index, who underwent emergency cholecystectomy.

Highlights

One of the indicators of the quality of surgical treatment is the course of the early postoperative period
The study selected 84 patients who were treated in the surgical department for acute surgical pathology, had grade I-II obesity lasting more than 10 years
Given that the operation itself and general anesthesia led to the pathogenetic mechanism of surgical stress, it was important to maintain the functional state of the endothelium at the most satisfactory level, which directly affected the state of POCD in the studied patients

Summary

Introduction

One of the indicators of the quality of surgical treatment is the course of the early postoperative period. It is considered smooth if successful [1, 2]. The causes of complications in the early postoperative period are many. Most often they are due to various objective reasons. One of such reasons is the inevitable impact on the body of surgical trauma [3, 4]. That is why there is a need to study the impact of the level of surgical trauma on the postoperative period

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Conclusion